Anti-COX1/Cyclooxygenase 1 antibody
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概述
- 产品描述Cytochrome c oxidase subunit I, COX1 (also designated COI, MTCO1 or oxidative phosphorylation (OxPhos) Complex IV, subunit I) is one of three mitochondrial DNA (mtDNA) encoded subunits (MTCO1-3) of respiratory Complex IV. Cytochrome c oxidase is a hetero-oligomeric enzyme composed of 13 subunits localized to the mitochondrial inner membrane and is the terminal enzyme complex of the electron transport chain. Complex IV catalyzes the reduction of molecular oxygen to water. The energy released is used to transport protons across the mitochondrial inner membrane. The resulting electro-chemical gradient is necessary for the synthesis of ATP. Complex IV contains 13 polypeptides; COX1, COX2 and COX3 (MTCO1-3) make up the catalytic core and are encoded by mtDNA while subunits IV, Va, Vb, VIa, VIb, VIc, VIIa, VIIb, VIIc and VIII are nuclear-encoded.
- 产品名称Anti-COX1/Cyclooxygenase 1 antibody
- 分子量69 kDa
- 种属反应性Human,Mouse
- 验证应用WB
- 抗体类型兔多抗
- 免疫原Synthetic peptide corresponding to C-terminal of Human COX1/Cyclooxygenase 1.
- 偶联Non-conjugated
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性能
- 形态Liquid
- 浓度2 mg/ml.
- 存放说明Store at +4℃ after thawing. Aliquot store at -20℃. Avoid repeated freeze / thaw cycles.
- 存储缓冲液1*PBS (pH7.4), 0.2% BSA, 25% Glycerol. Preservative: 0.05% Sodium Azide.
- 亚型IgG
- 纯化方式Peptide affinity purified.
- 亚细胞定位Microsome membrane, Endoplasmic reticulum membrane.
- 其它名称COX 1 antibody
COX 3 antibody
COX-1 antibody
COX1 antibody
Cox3 antibody
Cyclooxygenase 1 antibody
Cyclooxygenase 3, included antibody
Cyclooxygenase-1 antibody
EC 1.14.99.1 antibody
Partial COX1 proteins, included antibody
PCOX1 antibody
PGG/HS antibody
PGH synthase 1 antibody
PGH1_HUMAN antibody
PGHS-1 antibody
PGHS1 antibody
PHS 1 antibody
PHS1 antibody
Prostaglandin G/H synthase 1 antibody
Prostaglandin H2 synthase 1 antibody
Prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase) antibody
Prostaglandin-endoperoxide synthase 1 antibody
PTGHS antibody
PTGS1 antibody
more
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Fig1: Western blot analysis of COX1/Cyclooxygenase 1 on different lysates. Proteins were transferred to a PVDF membrane and blocked with 5% BSA in PBS for 1 hour at room temperature. The primary antibody was used at a 1:500 dilution in 5% BSA at room temperature for 2 hours. Goat Anti-Rabbit IgG - HRP Secondary Antibody (HA1001) at 1:5,000 dilution was used for 1 hour at room temperature.
Positive control:
Lane 1: 293T cell lysate, untreated
Lane 2: NIH/3T3 cell lysate, untreated
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