Anti-TSSC3 antibody
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概述
- 产品描述TSSC3 (Tumor-suppressing STF cDNA 3 protein), also known as PHLDA2 (pleckstrin homology-like domain family A member 2), BWR1C, HLDA2 or IPL, is a cytoplasmic protein that is involved in fetal and placental growth. Expressed at high levels in placenta and adult prostate and at low levels in liver, lung and brain, TSSC3 is an apoptosis-related protein that acts as a negative growth regulator and is expressed during normal human development. TSSC3, a protein expressed from the maternal allele, is imprinted on placenta, liver and fetal tissues during embryogenesis and is removed once development is complete. Defects or alterations in the gene encoding TSSC3 are associated with several afflictions such as lung, ovarian and breast cancer, rhabdomyosarcoma, Beckwith-Wiedemann syndrome, Wilms tumor, low birth weight and adrenocortical carcinoma. May act via its PH domain that competes with other PH domain-containing proteins, thereby preventing their binding to membrane lipids (By similarity).
- 产品名称Anti-TSSC3 antibody
- 分子量17 KDa
- 种属反应性Human,Mouse,Rat,Chicken,Pig,Cow,Horse
- 验证应用WB
- 抗体类型兔多抗
- 免疫原KLH conjugated synthetic peptide derived from human TSSC3 31-80/152
- 偶联Non-conjugated
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性能
- 形态Liquid
- 浓度1 mg/mL.
- 存放说明Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20℃. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4℃.
- 存储缓冲液0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
- 亚型IgG
- 纯化方式affinity purified by Protein A
- 亚细胞定位Cytoplasm. Membrane.
- 其它名称Beckwith Wiedemann syndrome chromosome region 1 candidate protein C
Beckwith-Wiedemann syndrome chromosomal region 1 candidate gene C protein
BRW 1C
BRW1C
BWR 1C
BWR1C
HLDA 2
HLDA2
Imprinted in placenta and liver
Imprinted in placenta and liver protein
IPL
p17 Beckwith Wiedemann region 1C
p17 BWR1C
p17-Beckwith-Wiedemann region 1 C
p17-BWR1C
PHLA2_HUMAN
PHLDA 2
PHLDA2
Pleckstrin homology like domain family A member 2
Pleckstrin homology-like domain family A member 2
TSSC 3
Tumor suppressing STF cDNA 3 protein
Tumor suppressing subchromosomal transferable fragment candidate gene 3 protein
Tumor suppressing subchromosomal transferable fragment cDNA 3
Tumor suppressing subtransferable candidate 3
Tumor supressing STF cDNA 3
Tumor-suppressing STF cDNA 3 protein
Tumor-suppressing subchromosomal transferable fragment candidate gene 3 protein.
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Fig1: Sample:
A549(Human) Cell Lysate at 30 ug
Primary: Anti-TSSC3 at 1/1000 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 17 kD
Observed band size: 18 kD
特别提示：本公司的所有产品仅可用于科研实验，严禁用于临床医疗及其他非科研用途！
