Anti-ZIP12 antibody
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概述
- 产品描述Acts as a zinc-influx transporter (Potential). May be partly involved in the outbreak of schizophrenia. On the basis of sequence homology, the human SLC39A12 gene has been included as a member of a family of zinc (Zn) transporters designated as the ZRT-IRT-like proteins (current designation SLC39). ZRT-IRT-like proteins act in concert with another family of transporters, known in non-mammalian organisms as cation diffusion facilitators and in mammals as zinc transporters (ZnT), to regulate the distribution of Zn in the extra- versus intracellular milieu and within cellular compartments. Hence the ZnT maintain Zn homeostasis that is critical for the normal functioning of tissues including the CNS.
- 产品名称Anti-ZIP12 antibody
- 分子量70 kDa
- 种属反应性Human,Mouse,Rat
- 验证应用WB,ICC,IHC-P
- 抗体类型兔多抗
- 免疫原Peptide
- 偶联Non-conjugated
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性能
- 形态Liquid
- 浓度1 mg/mL.
- 存放说明Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles.
- 存储缓冲液1*PBS (pH7.4), 0.2% BSA, 50% Glycerol. Preservative: 0.05% Sodium Azide.
- 亚型IgG
- 纯化方式Peptide affinity purified
- 亚细胞定位Membrane.
- 其它名称bA570F3.1 antibody
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LZT-Hs8 antibody
LZTHs8 antibody
MGC43205 antibody
MGC51099 antibody
S39AC_HUMAN antibody
SLC39A12 antibody
Solute carrier family 39 (metal ion transporter) member 12 antibody
Solute carrier family 39 (zinc transporter) member 12 antibody
Solute carrier family 39 member 12 antibody
Zinc transporter ZIP12 antibody
ZIP 12 antibody
ZIP-12 antibody
ZIP12 antibody
Zrt and Irt like protein 12 antibody
Zrt- and Irt-like protein 12 antibody
more
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应用
WB: 1:500-1:1,000
ICC: 1:50-1:200
IHC-P: 1:50-1:200
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Fig1: Western blot analysis of ZIP12 on HepG2 cell and rat lung tissue lysates using anti-ZIP12 antibody at 1/500 dilution.
Fig2: ICC staining ZIP12 in N2A cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.
Fig3: ICC staining ZIP12 in SH-SY5Y cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.
Fig4: Immunohistochemical analysis of paraffin-embedded mouse liver tissue using anti-ZIP12 antibody. Counter stained with hematoxylin.
Fig5: Immunohistochemical analysis of paraffin-embedded mouse brain tissue using anti-ZIP12 antibody. Counter stained with hematoxylin.
Fig6: Immunohistochemical analysis of paraffin-embedded mouse eyeball tissue using anti-ZIP12 antibody. Counter stained with hematoxylin.
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