Anti-ASBT/SLC10A2 antibody
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概述
- 产品描述This gene encodes a sodium/bile acid cotransporter. This transporter is the primary mechanism for uptake of intestinal bile acids by apical cells in the distal ileum. Bile acids are the catabolic product of cholesterol metabolism, so this protein is also critical for cholesterol homeostasis. Mutations in this gene cause primary bile acid malabsorption (PBAM); muatations in this gene may also be associated with other diseases of the liver and intestines, such as familial hypertriglyceridemia (FHTG). Plays a critical role in the sodium-dependent reabsorption of bile acids from the lumen of the small intestine. Plays a key role in cholesterol metabolism.
- 产品名称Anti-ASBT/SLC10A2 antibody
- 分子量38 KDa
- 种属反应性Human,Mouse,Rat,Dog,Cow,Horse,Rabbit
- 验证应用WB
- 抗体类型兔多抗
- 免疫原KLH conjugated synthetic peptide derived from human ASBT/SLC10A2 131-230/348
- 偶联Non-conjugated
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性能
- 形态Liquid
- 浓度1 mg/mL.
- 存放说明Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20℃. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4℃.
- 存储缓冲液0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
- 亚型IgG
- 纯化方式affinity purified by Protein A
- 亚细胞定位Membrane; Multi-pass membrane protein.
- 其它名称SLC10A2
Apical sodium dependent bile acid transporter
Apical sodium- dependent bile acid transporter
IBAT
ileal apical sodium-dependent bile acid transporter
Ileal sodium dependent bile acid transporter
Ileal sodium-dependent bile acid transporter
Ileal sodium/bile acid cotransporter
ISBT
Na+ bile acid cotransporter
Na+ dependent ileal bile acid transporter
NTCP2
Sodium/taurocholate cotransporting polypeptide, ileal
solute carrier family 10 (sodium/bile acid cotransporter family)
Solute carrier family 10 member 2.
more
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Fig1: Sample:
Liver (Mouse) Lysate at 40 ug
Primary: Anti-SLC10A2 at 1/300 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 38 kD
Observed band size: 43 kD
特别提示：本公司的所有产品仅可用于科研实验，严禁用于临床医疗及其他非科研用途！
