Anti-TWEAKR antibody
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概述
- 产品描述Fn14, the TWEAK receptor, is a recently identified member of the TNF receptor superfamily and is expressed on smooth muscle cells and endothelial cells. It is a weak inducer of apoptosis and promotes angiogenesis. Fn14 is a type 1 membrane protein. It associates with TRAF1 and TRAF2, and may modulate cellular adhesion to matrix proteins. Fn14 is highly expressed in heart, placenta and kidney, and moderately expressed in lung, skeletal muscle and pancreas. It is the smallest member of the TNF receptor (TNFR) superfamily described to date, and signals via recruitment of several different TNFR-associated factors.
- 产品名称Anti-TWEAKR antibody
- 分子量14 kDa
- 种属反应性Human,Mouse
- 验证应用ICC,IHC-P,FC
- 抗体类型兔多抗
- 免疫原Synthetic peptide within human TWEAKR aa 80-120.
- 偶联Non-conjugated
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性能
- 形态Liquid
- 浓度1 mg/mL.
- 存放说明Store at +4℃ after thawing. Aliquot store at -20℃. Avoid repeated freeze / thaw cycles.
- 存储缓冲液1*PBS (pH7.4), 0.2% BSA, 50% Glycerol. Preservative: 0.05% Sodium Azide.
- 亚型IgG
- 纯化方式Peptide affinity purified.
- 亚细胞定位Membrane.
- 其它名称CD 266 antibody
CD266 antibody
CD266 antigen antibody
FGF inducible 14 antibody
FGF-inducible 14 antibody
Fibroblast growth factor inducible immediate early response protein 14 antibody
Fibroblast growth factor-inducible immediate-early response protein 14 antibody
FN 14 antibody
FN14 antibody
TNFRSF 12A antibody
TNFRSF12A antibody
TNR12_HUMAN antibody
Tumor necrosis factor receptor superfamily member 12A antibody
TWEAK R antibody
Tweak receptor antibody
Tweak-receptor antibody
TweakR antibody
more
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应用
ICC: 1:50-1:200
IHC-P: 1:50-1:200
FC: 1:50-1:100
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Fig1: ICC staining TWEAKR in MCF-7 cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.
Fig2: ICC staining TWEAKR in SiHa cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.
Fig3: Immunohistochemical analysis of paraffin-embedded human colon cancer tissue using anti-TWEAKR antibody. Counter stained with hematoxylin.
Fig4: Immunohistochemical analysis of paraffin-embedded human placenta tissue using anti-TWEAKR antibody. Counter stained with hematoxylin.
Fig5: Immunohistochemical analysis of paraffin-embedded mouse testis tissue using anti-TWEAKR antibody. Counter stained with hematoxylin.
Fig6: Flow cytometric analysis of 293T cells with TWEAKR antibody at 1/100 dilution (red) compared with an unlabelled control (cells without incubation with primary antibody; black). Alexa Fluor 488-conjugated goat anti-rabbit IgG was used as the secondary antibody.
特别提示：本公司的所有产品仅可用于科研实验，严禁用于临床医疗及其他非科研用途！
