Anti-SLC7A5 antibody
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概述
- 产品描述Sodium-independent, high-affinity transport of large neutral amino acids such as phenylalanine, tyrosine, leucine, arginine and tryptophan, when associated with SLC3A2/4F2hc. Involved in cellular amino acid uptake. Acts as an amino acid exchanger. Involved in the transport of L-DOPA across the blood-brain barrier, and that of thyroid hormones triiodothyronine (T3) and thyroxine (T4) across the cell membrane in tissues such as placenta. Plays a role in neuronal cell proliferation (neurogenesis) in brain. Involved in the uptake of methylmercury (MeHg) when administered as the L-cysteine or D,L-homocysteine complexes, and hence plays a role in metal ion homeostasis and toxicity. Involved in the cellular activity of small molecular weight nitrosothiols, via the stereoselective transport of L-nitrosocysteine (L-CNSO) across the transmembrane. May play an important role in high-grade gliomas. Mediates blood-to-retina L-leucine transport across the inner blood-retinal barrier which in turn may play a key role in maintaining large neutral amino acids as well as neurotransmitters in the neural retina. Acts as the major transporter of tyrosine in fibroblasts.
- 产品名称Anti-SLC7A5 antibody
- 分子量55 KDa
- 种属反应性Human,Mouse,Rat,Chicken,Dog,Cow,Rabbit
- 验证应用WB
- 抗体类型兔多抗
- 免疫原KLH conjugated synthetic peptide derived from human SLC7A5 101-200/507
- 偶联Non-conjugated
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性能
- 形态Liquid
- 浓度1 mg/mL.
- 存放说明Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20℃. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4℃.
- 存储缓冲液0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
- 亚型IgG
- 纯化方式affinity purified by Protein A
- 亚细胞定位Cytoplasm, cytosol. Apical cell membrane. Located to the plasma membrane by SLC3A2/4F2hc. Localized to the apical membrane of placental syncytiophoblastic cells. Expressed in both luminal and abluminal membranes of brain capillary endothelial cells.
- 其它名称LAT1
4F2 LC
4F2 light chain
SLC7A5
4F2LC
CD98
CD98 light chain
CD98LC
D16S469E
DC49
E16
hLAT1
Integral membrane protein E16
L type amino acid transporter
L type amino acid transporter 1
L-type amino acid transporter 1
Large neutral amino acids transporter 1
Large neutral amino acids transporter
Large neutral amino acids transporter small subunit 1
LAT1_HUMAN
Membrane protein E16
MPE16
Slc7a5
Sodium independent neutral amino acid transporter
Sodium independent neutral amino acid transporter LAT1
Solute carrier family 7 (cationic amino acid transporter y+ system) member 5
Solute carrier family 7 member 5
TA1
Tumor associated protein 1
y+ system cationic amino acid transporter.
more
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Fig1: Sample: Brain (Rat) Lysate at 40 ug
Primary: Anti-SLC7A5 at 1/300 dilution
Secondary: HRP conjugated Goat-Anti-rabbit IgG (bs-0295G-HRP) at 1/5000 dilution
Predicted band size: 55 kD
Observed band size: 55 kD
特别提示：本公司的所有产品仅可用于科研实验，严禁用于临床医疗及其他非科研用途！
