Anti-KOR-1 antibody
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概述
- 产品描述OPRK1 encodes an opioid receptor, which is a member of the 7 transmembrane-spanning G protein-coupled receptor family. It functions as a receptor for endogenous ligands, as well as a receptor for various synthetic opioids. Ligand binding results in inhibition of adenylate cyclase activity and neurotransmitter release. This opioid receptor plays a role in the perception of pain and mediating the hypolocomotor, analgesic and aversive actions of synthetic opioids. Variations in this gene have also been associated with alcohol dependence and opiate addiction. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. A recent study provided evidence for translational readthrough in this gene and expression of an additional C-terminally extended isoform via the use of an alternative in-frame translation termination codon.
- 产品名称Anti-KOR-1 antibody
- 分子量42 kDa
- 种属反应性Mouse,Rat
- 验证应用IHC-P,WB
- 抗体类型兔多抗
- 免疫原The antiserum was produced against synthesized peptide derived from mouse KOR-1. AA range:331-380
- 偶联Non-conjugated
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性能
- 形态Liquid
- 浓度1 mg/mL.
- 存放说明Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles.
- 存储缓冲液Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
- 亚型IgG
- 纯化方式Immunogen affinity purified.
- 其它名称OPRK1 antibody; OPRK antibody; Kappa-type opioid receptor antibody; K-OR-1 antibody; KOR-1 antibody;
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应用
WB: 1:500-1:2000
IHC-P: 1:100-1:300
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