Anti-Laminin β-2 antibody
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概述
- 产品描述Laminins, a family of extracellular matrix glycoproteins, are the major noncollagenous constituent of basement membranes. They have been implicated in a wide variety of biological processes including cell adhesion, differentiation, migration, signaling, neurite outgrowth and metastasis. Laminins, composed of 3 non identical chains: laminin alpha, beta and gamma (formerly A, B1, and B2, respectively), form a cruciform structure consisting of 3 short arms, each formed by a different chain, and a long arm composed of all 3 chains. Each laminin chain is a multidomain protein encoded by a distinct gene. Several isoforms of each chain have been described. Different alpha, beta and gamma chain isomers combine to give rise to different heterotrimeric laminin isoforms which are designated by Arabic numerals in the order of their discovery, i. e. alpha1beta1gamma1 heterotrimer is laminin 1. The biological func
- 产品名称Anti-Laminin β-2 antibody
- 分子量210 kDa
- 种属反应性Human, Mouse, Rat
- 验证应用WB, IHC-P
- 抗体类型兔多抗
- 免疫原The antiserum was produced against synthesized peptide derived from human LAMB2. AA range:61-110
- 偶联Non-conjugated
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性能
- 形态Liquid
- 浓度1 mg/mL.
- 存放说明Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles.
- 存储缓冲液Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
- 亚型IgG
- 纯化方式Immunogen affinity purified.
- 其它名称LAMB2 antibody; LAMS antibody; Laminin subunit beta-2 antibody; Laminin B1s chain antibody; Laminin-11 subunit beta antibody; Laminin-14 subunit beta antibody; Laminin-15 subunit beta antibody; Laminin-3 subunit beta antibody; Laminin-4 subunit beta antibody; Laminin-7 subunit beta antibody; Laminin-9 subunit beta antibody; S-laminin sub antibody;
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应用
WB: 1:500-1:2000
IHC-P: 1:100-1:300
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Fig1: Immunohistochemical analysis of paraffin-embedded Human lung cancer. Antibody was diluted at 1:100(4°,overnight). High-pressure and temperature Tris-EDTA,pH8.0 was used for antigen retrieval. Negetive contrl (right) obtaned from antibody was pre-absorbed by immunogen peptide.
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