Anti-Nucleolin antibody
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概述
- 产品描述Nucleolin is a multi-functional protein that is one of the major components of the nucleoli. It plays an essential role in various steps of ribosome biogenesis including rRNA synthesis, processing of pre-rRNA, pre-ribosomal RNA assembly, and transport of ribosomal proteins out of the nucleus. While the main function of nucleolin is ribosome biogenesis, it plays an important role in various other nuclear activities. Down regulation of nucleolin leads to increased expression of p53, defects in genome duplication, and a delay at prometaphase during mitosis leading to cell cycle arrest.
- 产品名称Anti-Nucleolin antibody
- 分子量~100kDa
- 种属反应性Human,Mouse
- 验证应用WB,ICC
- 抗体类型兔多抗
- 免疫原peptide
- 偶联Non-conjugated
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性能
- 形态Liquid
- 浓度1 mg/mL.
- 存放说明Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles.
- 存储缓冲液1*PBS (pH7.4), 0.2% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
- 亚型IgG
- 纯化方式Immunogen affinity purified
- 亚细胞定位Cell nucleus, cytoplasm
- 其它名称
- C23 antibody
- FLJ45706 antibody
- MS1116 antibody
more
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应用
WB: 1:1,000
ICC: 1:100-1:200
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Fig1: Western blot analysis on different cell lysates using anti-nucleolin rabbit polyclonal antibodies.
Fig2: ICC staining nucleolin in mouse embryonic stem cells (red). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS and counterstained with DAPI in order to highlight the nucleus (blue).
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