Anti-USP14 antibody
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概述
- 产品描述Proteasome-associated deubiquitinase which releases ubiquitin from the proteasome targeted ubiquitinated proteins. Ensures the regeneration of ubiquitin at the proteasome. Is a reversibly associated subunit of the proteasome and a large fraction of proteasome-free protein exists within the cell. Required for the degradation of the chemokine receptor CXCR4 which is critical for CXCL12-induced cell chemotaxis. Serves also as a physiological inhibitor of endoplasmic reticulum-associated degradation under the non-stressed condition by inhibiting the degradation of unfolded endoplasmic reticulum proteins via interaction with ERN1. Indispensable for synaptic development and function at neuromuscular junctions. Plays a role in the innate immune defense against viruses by stabilizing the viral DNA sensor CGAS and thus inhibiting its autophagic degradation.
- 产品名称Anti-USP14 antibody
- 分子量56 kDa
- 种属反应性Human
- 验证应用WB,FC
- 抗体类型兔多抗
- 免疫原Recombinant protein within human USP14 aa 200-450.
- 偶联Non-conjugated
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性能
- 形态Liquid
- 浓度1 mg/mL.
- 存放说明Store at +4℃ after thawing. Aliquot store at -20℃. Avoid repeated freeze / thaw cycles.
- 存储缓冲液1*PBS (pH7.4), 0.2% BSA, 50% Glycerol. Preservative: 0.05% Sodium Azide.
- 亚型IgG
- 纯化方式Protein affinity purified.
- 亚细胞定位Plasma membrane.
- 其它名称Deubiquitinating enzyme 14 antibody
TGT antibody
tRNA guanine transglycosylase 60 kD subunit antibody
tRNA guanine transglycosylase antibody
Ubiquitin carboxyl terminal hydrolase 14 antibody
Ubiquitin carboxyl-terminal hydrolase 14 antibody
Ubiquitin specific peptidase 14 antibody
Ubiquitin specific processing protease 14 antibody
Ubiquitin specific protease 14 antibody
Ubiquitin thiolesterase 14 antibody
Ubiquitin-specific-processing protease 14 antibody
UBP14_HUMAN antibody
USP 14 antibody
USP14 antibody
more
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应用
WB: 1:500-1:1,000
FC: 1:50-1:100
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Fig1: Western blot analysis of USP14 on Daudi cell lysate using anti-USP14 antibody at 1/500 dilution.
Fig2: Flow cytometric analysis of SiHa cells with USP14 antibody at 1/100 dilution (red) compared with an unlabelled control (cells without incubation with primary antibody;black). Alexa Fluor 488-conjugated goat anti-rabbit IgG was used as the secondary antibody.
特别提示：本公司的所有产品仅可用于科研实验，严禁用于临床医疗及其他非科研用途！
