Anti-UBE2D2 antibody
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概述
- 产品描述Accepts ubiquitin from the E1 complex and catalyzes its covalent attachment to other proteins. In vitro catalyzes 'Lys-48'-linked polyubiquitination. Mediates the selective degradation of short-lived and abnormal proteins. Functions in the E6/E6-AP-induced ubiquitination of p53/TP53. Mediates ubiquitination of PEX5 and autoubiquitination of STUB1 and TRAF6. Involved in the signal-induced conjugation and subsequent degradation of NFKBIA, FBXW2-mediated GCM1 ubiquitination and degradation, MDM2-dependent degradation of p53/TP53 and the activation of MAVS in the mitochondria by DDX58/RIG-I in response to viral infection. Essential for viral activation of IRF3.
- 产品名称Anti-UBE2D2 antibody
- 分子量17 KDa
- 种属反应性Human,Mouse,Rat,Chicken,Cow,Horse,Rabbit,Sheep
- 验证应用WB
- 抗体类型兔多抗
- 免疫原KLH conjugated synthetic peptide derived from human UBE2D2 31-130/147
- 偶联Non-conjugated
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性能
- 形态Liquid
- 浓度1 mg/mL.
- 存放说明Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20℃. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4℃.
- 存储缓冲液0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
- 亚型IgG
- 纯化方式affinity purified by Protein A
- 其它名称PUBC 1
PUBC1
UB2D2_HUMAN
UBC 4
UBC 4/5
UBC4
UBC4/5
UBC4/5 homolog yeast
UBCH 5B
UBCH5B
UBE2D2
Ubiquitin carrier protein
Ubiquitin carrier protein D2
Ubiquitin conjugating enzyme E2 17 kDa 2
Ubiquitin conjugating enzyme E2 D2
Ubiquitin conjugating enzyme E2D 2 (homologous to yeast UBC4/5)
Ubiquitin conjugating enzyme E2D 2 (UBC4/5 homolog yeast)
Ubiquitin conjugating enzyme E2D 2
Ubiquitin protein ligase D2
Ubiquitin-conjugating enzyme E2 D2
Ubiquitin-conjugating enzyme E2(17)KB 2
Ubiquitin-conjugating enzyme E2-17 kDa 2
Ubiquitin-protein ligase D2
E2(17)KB2.
more
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Fig1: Sample: Hela Cell (Human) Lysate at 40 ug
Primary: Anti-UBE2D2 at 1/300 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 17 kD
Observed band size: 17 kD
Fig2: Sample: Lung (Mouse) Lysate at 40 ug
Primary: Anti-UBE2D2 at 1/300 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 17 kD
Observed band size: 17 kD
特别提示:本公司的所有产品仅可用于科研实验,严禁用于临床医疗及其他非科研用途!