Anti-USP36 antibody
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概述
- 产品描述Ubiquitin-specific protease 36 is an enzyme that in humans is encoded by the USP36 gene. This gene encodes a member of the ubiquitin-specific protease family of proteases that is a deubiquitinating enzyme (DUB) with His and Cys domains. This protein is located in the nucleoli and deubuquitinate nucleophosmin and fibrillarin. May be required for maintaining multiple types of adult stem cells. May function as a transcriptional repressor by continually deubiquiting histone H2B at the promoters of genes critical for cellular differentiation, thereby preventing histone H3 'Lys-4' trimethylation (H3K4).
- 产品名称Anti-USP36 antibody
- 分子量123 kDa
- 种属反应性Human
- 验证应用ICC,IHC-P
- 抗体类型兔多抗
- 免疫原Peptide
- 偶联Non-conjugated
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性能
- 形态Liquid
- 浓度1 mg/mL.
- 存放说明Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles.
- 存储缓冲液1*PBS (pH7.4), 0.2% BSA, 50% Glycerol. Preservative: 0.05% Sodium Azide.
- 亚型IgG
- 纯化方式Peptide affinity purified
- 亚细胞定位Nucleus.
- 其它名称Deubiquitinating enzyme 1 antibody
Deubiquitinating enzyme 36 antibody
DUB1 antibody
FLJ12851 antibody
KIAA1453 antibody
Ubiquitin carboxyl-terminal hydrolase 36 antibody
Ubiquitin specific peptidase 36 antibody
Ubiquitin specific processing protease 36 antibody
Ubiquitin thioesterase 36 antibody
Ubiquitin thiolesterase 36 antibody
Ubiquitin-specific-processing protease 36 antibody
UBP36_HUMAN antibody
Usp36 antibody
more
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应用
ICC: 1:50-1:200
IHC-P: 1:50-1:200
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Fig1: ICC staining USP36 in A549 cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.
Fig2: ICC staining USP36 in Hela cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.
Fig3: ICC staining USP36 in LOVO cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.
Fig4: Immunohistochemical analysis of paraffin-embedded human liver cancer tissue using anti-USP36 antibody. Counter stained with hematoxylin.
Fig5: Immunohistochemical analysis of paraffin-embedded human spleen tissue using anti-USP36 antibody. Counter stained with hematoxylin.
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