Anti-Factor XIIa heavy chain antibody
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概述
- 产品描述Factor XII is a serum glycoprotein that participates in the initiation of blood coagulation, fibrinolysis, and the generation of bradykinin and angiotensin. Prekallikrein is cleaved by factor XII to form kallikrein, which then cleaves factor XII first to alpha-factor XIIa and then trypsin cleaves it to beta-factor XIIa. Alpha-factor XIIa activates factor XI to factor XIa.
- 产品名称Anti-Factor XIIa heavy chain antibody
- 分子量40/68 KDa
- 种属反应性Human,Mouse,Rat,Dog,Cow,Horse,Sheep
- 验证应用WB
- 抗体类型兔多抗
- 免疫原KLH conjugated synthetic peptide derived from human Coagulation factor XIIa heavy chain 31-130/615
- 偶联Non-conjugated
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性能
- 形态Liquid
- 浓度1 mg/mL.
- 存放说明Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20℃. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4℃.
- 存储缓冲液0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
- 亚型IgG
- 纯化方式affinity purified by Protein A
- 亚细胞定位Secreted.
- 其它名称Factor XII
Coagulation factor XII
Factor XII heavy chain
Coagulation factor XIIa heavy chain
F12
F12 deficiency
FA12_HUMAN
Factor XII deficiency
HAE3
HAEX
HAF
HAF deficiency
Hageman factor
Coagulation factor XIIa heavy chain.
more
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Fig1: Sample: 293T Cell (Human) Lysate at 40 ug
Primary: Anti-Factor XII heavy chain at 1/300 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 40/68 kD
Observed band size: 38 kD
Fig2: Sample: HepG2 Cell (Human) Lysate at 40 ug
Primary: Anti-Factor XII heavy chainat 1/300 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 40/68 kD
Observed band size: 38 kD
Fig3: Sample:
U937(Human) Cell Lysate at 30 ug
Primary: Anti- Factor XIIa heavy chain at 1/1000 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 40/68 kD
Observed band size: 68 kD
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