Anti-FAIM3 antibody

Anti-FAIM3 antibody

• 概述

• 产品描述May play a role in the immune system processes. Protects cells from FAS-, TNF alpha- and FADD-induced apoptosis without increasing expression of the inhibitors of apoptosis BCL2 and BCLXL. Seems to activate an inhibitory pathway that prevents CASP8 activation following FAS stimulation, rather than blocking apoptotic signals downstream. May inhibit FAS-induced apoptosis by preventing CASP8 processing through CFLAR up-regulation.
• 产品名称Anti-FAIM3 antibody
• 分子量41 KDa
• 种属反应性Human
• 验证应用WB
• 抗体类型兔多抗
• 免疫原KLH conjugated synthetic peptide derived from human FAIM3 51-150/390
• 偶联Non-conjugated

• 性能

• 形态Liquid
• 浓度1 mg/mL.
• 存放说明Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20℃. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4℃.
• 存储缓冲液0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
• 亚型IgG
• 纯化方式affinity purified by Protein A
• 亚细胞定位Isoform 1: Membrane; Single-pass membrane protein. Isoform 3: Secreted. Note=Detected in the serum.
• 其它名称Faim3
  FAIM3_HUMAN
  Fas apoptotic inhibitory molecule 3
  Fc mu receptor
  FCMR
  IgM Fc receptor
  Immunoglobulin mu Fc receptor
  Regulator of Fas induced apoptosis
  Regulator of Fas-induced apoptosis Toso
  TOSO.
  more

• 应用

  WB:1:500-2000

•  

  

  Fig1: Sample:
  Hela(Human) Cell Lysate at 30 ug
  Primary: Anti-FAIM3 at 1/300 dilution
  Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
  Predicted band size: 41 kD
  Observed band size: 31 kD

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