Anti-Fusion glycoprotein F0 antibody
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概述
- 产品描述During virus entry, induces fusion of viral and cellular membranes leading to delivery of the nucleocapsid into the cytoplasm. The fusogenic activity is inactive untill entry into host cell endosome, where a furin-like protease cleaves off a small peptide between F1 and F2. Interacts directly with heparan sulfate and may participate in virus attachment. Furthermore, the F2 subunit was identifed as the major determinant of RSV host cell specificity. Later in infection, proteins F expressed at the plasma membrane of infected cells can mediate fusion with adjacent cells to form syncytia, a cytopathic effect that could lead to tissue necrosis. The fusion protein is also able to trigger p53-dependent apoptosis.
- 产品名称Anti-Fusion glycoprotein F0 antibody
- 分子量59 kDa
- 种属反应性Avian avulavirus 1
- 验证应用WB,ELISA
- 抗体类型兔多抗
- 免疫原Peptide
- 偶联Non-conjugated
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性能
- 形态Liquid
- 浓度1 mg/mL.
- 存放说明Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles.
- 存储缓冲液1*PBS (pH7.4), 0.2% BSA, 50% Glycerol. Preservative: 0.05% Sodium Azide.
- 亚型IgG
- 纯化方式Peptide affinity purified
- 亚细胞定位Host cell membrane. Virion membrane.
- 其它名称F antibody
Fusion glycoprotein F0 antibody
Protein F antibody
RSV Fusion (F) Glycoprotein antibody
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应用
WB: 1:500-1,000
ELISA: 1:5,000-1:10,000
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Fig1: Western blot analysis of Fusion glycoprotein F0 on Fusion glycoprotein F0 transfected HEK293 cell lysates using anti- Fusion glycoprotein F0 antibody at 1/500 dilution.
特别提示：本公司的所有产品仅可用于科研实验，严禁用于临床医疗及其他非科研用途！
