Anti-CCBR1 antibody
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概述
- 产品描述This gene encodes a member of a heteromeric, sodium-independent, anionic amino acid transport system that is highly specific for cysteine and glutamate. In this system, designated Xc(-), the anionic form of cysteine is transported in exchange for glutamate. This protein has been identified as the predominant mediator of Kaposi sarcoma-associated herpesvirus fusion and entry permissiveness into cells. Also, increased expression of this gene in primary gliomas (compared to normal brain tissue) was associated with increased glutamate secretion via the XCT channels, resulting in neuronal cell death. Sodium-independent, high-affinity exchange of anionic amino acids with high specificity for anionic form of cystine and glutamate.
- 产品名称Anti-CCBR1 antibody
- 分子量55 KDa
- 种属反应性Human,Mouse,Rat,Dog,Pig,Cow,Horse,Sheep
- 验证应用WB
- 抗体类型兔多抗
- 免疫原KLH conjugated synthetic peptide derived from human xCT/CCBR1 201-300/501
- 偶联Non-conjugated
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性能
- 形态Liquid
- 浓度1 mg/mL.
- 存放说明Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20℃. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4℃.
- 存储缓冲液0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
- 亚型IgG
- 纯化方式affinity purified by Protein A
- 亚细胞定位Membrane; Multi-pass membrane protein.
- 其它名称Amino acid transport system xc xCT antibody
Amino acid transport system xc- antibody Calcium channel blocker resistance protein CCBR1
Calcium channel blocker resistance protein CCBR1 antibody
CCBR1
Cysteine/glutamate transporter antibody
cystine/glutamate transporter
SLC7A11
Solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11
solute carrier family 7
Solute carrier family 7 member 11
Solute carrier family 7, (cationic amino acid transporter, y+ system) member 11
xCT
XCT_HUMAN.
more
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Fig1: Sample:
U-87MG(Human) Cell Lysate at 30 ug
Primary: Anti-CCBR1 at 1/1000 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 55 kD
Observed band size: 55 kD
特别提示：本公司的所有产品仅可用于科研实验，严禁用于临床医疗及其他非科研用途！
