Anti-GPX2 antibody
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概述
- 产品描述Glutathione peroxidase 2 is an enzyme that in humans is encoded by the GPX2 gene. This gene is a member of the glutathione peroxidase family encoding a selenium-dependent glutathione peroxidase that is one of two isoenzymes responsible for the majority of the glutathione-dependent hydrogen peroxide-reducing activity in the epithelium of the gastrointestinal tract. Studies in knockout mice indicate that mRNA expression levels respond to luminal microflora, suggesting a role of the ileal glutathione peroxidases in preventing inflammation in the GI tract. The antioxidant enzyme glutathione peroxidase 2 (Gpx2) is one out of eight known glutathione peroxidases (Gpx1-8) in humans. Mammalian Gpx1, GPx2 (this protein), Gpx3, and Gpx4 have been shown to be selenium-containing enzymes, whereas Gpx6 is a selenoprotein in humans with cysteine-containing homologues in rodents. In selenoproteins, the 21st amino acid selenocysteine is inserted in the nascent polypeptide chain during the process of translational recoding of the UGA stop codon.
- 产品名称Anti-GPX2 antibody
- 分子量22 KDa
- 种属反应性Human,Mouse,Rat,Dog,Cow,Horse,Rabbit,Sheep
- 验证应用WB
- 抗体类型兔多抗
- 免疫原KLH conjugated synthetic peptide derived from human GPX2/Glutathione Peroxidase 2 41-140/190
- 偶联Non-conjugated
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性能
- 形态Liquid
- 浓度1 mg/mL.
- 存放说明Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
- 存储缓冲液0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
- 亚型IgG
- 纯化方式Affinity purified by Protein A
- 亚细胞定位Cytoplasm. Mainly cytoplasmic.
- 其它名称Gastrointestinal glutathione peroxidase
GI GPx
Glutathione peroxidase 2 (gastrointestinal)
Glutathione peroxidase 2
Glutathione peroxidase gastrointestinal
Glutathione peroxidase related protein 2
Glutathione peroxidase-gastrointestinal
Glutathione peroxidase-related protein 2
GPRP
GPRP-2
GPx 2
GPx-2
GPx-GI
GPX2
GPX2_HUMAN
GSHPx 2
GSHPx GI
GSHPx-2
GSHPx-GI.
more
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Fig1: Sample:
Liver (Mouse) Lysate at 40 ug
Primary: Anti-GPX2 at 1/1000 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 22 kD
Observed band size: 22 kD
特别提示：本公司的所有产品仅可用于科研实验，严禁用于临床医疗及其他非科研用途！
