Anti-NPY2R antibody
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概述
- 产品描述NPY2 receptor is a member of GPCR1 family and is localized primarily on Neuropeptide Y-expressing neurons in the hypothalamic region of the brain. It binds specifically to the C-terminal of Neuropeptide Y and is responsible for regulation of presynaptic relase of noradrenaline. Reports suggest a probable role of NPY2 receptor in regulation of feeding behavior, energy homeostasis and also in regulating cardiovascular system. Variations in the NPY2 receptor genes have been linked to occurrence of Diabetes. Receptor for neuropeptide Y and peptide YY. The rank order of affinity of this receptor for pancreatic polypeptides is PYY > NPY > PYY (3-36) > NPY (2-36) > [Ile-31, Gln-34] PP > [Leu-31, Pro-34] NPY > PP, [Pro-34] PYY and NPY free acid.
- 产品名称Anti-NPY2R antibody
- 分子量43 KDa
- 种属反应性Human,Mouse,Rat,Pig
- 验证应用WB
- 抗体类型兔多抗
- 免疫原KLH conjugated synthetic peptide derived from human NPY2R 301-381/381
- 偶联Non-conjugated
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性能
- 形态Liquid
- 浓度1 mg/mL.
- 存放说明Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20℃. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4℃.
- 存储缓冲液0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
- 亚型IgG
- 纯化方式Affinity purified by Protein A
- 亚细胞定位Cell membrane.
- 其它名称Neuropeptide Y Receptor Type 2
Neuropeptide Y receptor Y2
NPY-Y2 receptor
NPY2R_HUMAN.
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Fig1: Sample: A549 Cell Lysate at 30 ug
Primary: Anti- NPY2R at 1/300 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 43 kD
Observed band size: 43 kD
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