Anti-Smad2/3 (Acetyl-Lys19) antibody
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概述
- 产品描述The protein encoded by this gene belongs to the SMAD, a family of proteins similar to the gene products of the Drosophila gene 'mothers against decapentaplegic' (Mad) and the C. elegans gene Sma. SMAD proteins are signal transducers and transcriptional modulators that mediate multiple signaling pathways. This protein mediates the signal of the transforming growth factor (TGF)-beta, and thus regulates multiple cellular processes, such as cell proliferation, apoptosis, and differentiation. This protein is recruited to the TGF-beta receptors through its interaction with the SMAD anchor for receptor activation (SARA) protein. In response to TGF-beta signal, this protein is phosphorylated by the TGF-beta receptors. The phosphorylation induces the dissociation of this protein with SARA and the association with the family member SMAD4. The association with SMAD4 is important for the translocation
- 产品名称Anti-Smad2/3 (Acetyl-Lys19) antibody
- 分子量60 kDa
- 种属反应性Human,Mouse,Rat
- 验证应用IHC-P,WB
- 抗体类型兔多抗
- 免疫原Synthesized peptide derived from human Smad2/3 (Acetyl-Lys19)
- 偶联Non-conjugated
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性能
- 形态Liquid
- 浓度1 mg/mL.
- 存放说明Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles.
- 存储缓冲液Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
- 亚型IgG
- 纯化方式Immunogen affinity purified.
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应用
IHC-P: 1:50-200
WB: 1:500-1:2000
特别提示：本公司的所有产品仅可用于科研实验，严禁用于临床医疗及其他非科研用途！
