Anti-Cav3.2 antibody
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概述
- 产品描述This gene encodes a T-type member of the alpha-1 subunit family, a protein in the voltage-dependent calcium channel complex. Calcium channels mediate the influx of calcium ions into the cell upon membrane polarization and consist of a complex of alpha-1, alpha-2/delta, beta, and gamma subunits in a 1:1:1:1 ratio. The alpha-1 subunit has 24 transmembrane segments and forms the pore through which ions pass into the cell. There are multiple isoforms of each of the proteins in the complex, either encoded by different genes or the result of alternative splicing of transcripts. Alternate transcriptional splice variants, encoding different isoforms, have been characterized for the gene described here. Studies suggest certain mutations in this gene lead to childhood absence epilepsy (CAE).
- 产品名称Anti-Cav3.2 antibody
- 分子量260 kDa
- 种属反应性Human, Rat, Mouse
- 验证应用IHC-P
- 抗体类型兔多抗
- 免疫原Synthetic Peptide of Cav3.2
- 偶联Non-conjugated
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性能
- 形态Liquid
- 浓度1 mg/mL.
- 存放说明Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles.
- 存储缓冲液Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
- 亚型IgG
- 纯化方式Immunogen affinity purified.
- 其它名称CACNA1H antibody; Voltage-dependent T-type calcium channel subunit alpha-1H antibody; Low-voltage-activated calcium channel alpha1 3.2 subunit antibody; Voltage-gated calcium channel subunit alpha Cav3.2 antibody;
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Fig1: Immunohistochemical analysis of paraffin-embedded Rat Brain Tissue using Cav3.2Rabbit pAb diluted at 1:200.
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