Anti-CdcA3 antibody
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概述
- 产品描述domain:The KEN box is required for the association with the APC/C-Cdh1 complex. F-box-like protein which is required for entry into mitosis. Acts by participating to E3 ligase complexes that mediate the ubiquitination and degradation of WEE1 kinase at G2/M phase. pathway:Protein modification; protein ubiquitination. PTM:Phosphorylated upon DNA damage, probably by ATM or ATR. PTM:Ubiquitinated and degraded by the APC/C-Cdh1 complex. subunit:Interacts with SKP1A. Part of a SCF (SKP1-cullin-F-box) protein ligase complex.
- 产品名称Anti-CdcA3 antibody
- 分子量28 kDa
- 种属反应性Human, Mouse, Rat
- 验证应用WB, IHC-P, IF
- 抗体类型兔多抗
- 免疫原The antiserum was produced against synthesized peptide derived from human CDCA3. AA range:219-268
- 偶联Non-conjugated
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性能
- 形态Liquid
- 浓度1 mg/mL.
- 存放说明Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles.
- 存储缓冲液Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
- 亚型IgG
- 纯化方式Immunogen affinity purified.
- 其它名称CDCA3 antibody; C8 antibody; GRCC8 antibody; TOME1 antibody; Cell division cycle-associated protein 3 antibody; Gene-rich cluster protein C8 antibody; Trigger of mitotic entry protein 1 antibody; TOME-1 antibody;
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应用
WB: 1:500-1:2000
IHC-P: 1:100-1:300
IF: 1:100-1:500
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Fig1: Western Blot analysis of various cells using CdcA3 Polyclonal Antibody
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