Anti-SARM1 antibody
-
概述
- 产品描述caution:Was initially reported to contain ARM repeats (PubMed:11386760). Such repeats are however not predicted by any detection method. Involved in innate immnune response. Acts as a negative regulator of TICAM1/TRIF-dependent Toll-like receptor signaling by inhibiting induction of TLR3- and TLR4-dependent genes. Specifically blocks TICAM1/TRIF-dependent transcription-factor activation and gene induction, without affecting the MYD88-dependent pathway or non-TLR signaling. Negative regulator of NF-kappa-B and IRF activation. Contains 1 TIR domain. Contains 2 SAM (sterile alpha motif) domains. subunit:Interacts with TICAM1/TRIF and thereby interferes with TICAM1/TRIF function. tissue specificity:Predominantly expressed in kidney and liver. Expressed at lower level in placenta.
- 产品名称Anti-SARM1 antibody
- 分子量79 kDa
- 种属反应性Human,Mouse
- 验证应用WB
- 抗体类型兔多抗
- 免疫原Synthesized peptide derived from human protein . at AA range: 281-330
- 偶联Non-conjugated
-
性能
- 形态Liquid
- 浓度1 mg/mL.
- 存放说明Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles.
- 存储缓冲液Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
- 亚型IgG
- 纯化方式Immunogen affinity purified.
-
特别提示：本公司的所有产品仅可用于科研实验，严禁用于临床医疗及其他非科研用途！
