Anti-ATRX antibody
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概述
- 产品描述The protein encoded by this gene contains an ATPase/helicase domain, and thus it belongs to the SWI/SNF family of chromatin remodeling proteins. This protein is found to undergo cell cycle-dependent phosphorylation, which regulates its nuclear matrix and chromatin association, and suggests its involvement in the gene regulation at interphase and chromosomal segregation in mitosis. Mutations in this gene are associated with an X-linked mental retardation (XLMR) syndrome most often accompanied by alpha-thalassemia (ATRX) syndrome. These mutations have been shown to cause diverse changes in the pattern of DNA methylation, which may provide a link between chromatin remodeling, DNA methylation, and gene expression in developmental processes. Multiple alternatively spliced transcript variants encoding distinct isoforms have been reported.
- 产品名称Anti-ATRX antibody
- 种属反应性Human,Mouse
- 验证应用IF
- 抗体类型兔多抗
- 免疫原The antiserum was produced against synthesized peptide derived from human ATRX. AA range:111-160
- 偶联Non-conjugated
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性能
- 形态Liquid
- 浓度1 mg/mL.
- 存放说明Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles.
- 存储缓冲液Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
- 亚型IgG
- 纯化方式Immunogen affinity purified.
- 其它名称ATRX antibody; RAD54L antibody; XH2 antibody; Transcriptional regulator ATRX antibody; ATP-dependent helicase ATRX antibody; X-linked helicase II antibody; X-linked nuclear protein antibody; XNP antibody; Znf-HX antibody;
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