Anti-CRMP-3 antibody
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概述
- 产品描述disease:Antibodies against post-translationally modified DPYSL4, also called anti-CV2 autoantibodies, are present in sera from patients with paraneoplastic neurological diseases (PND). PND are disorders of the nervous system associated with various systemic cancers which are not a direct result of the tumor mass or metastasis, but attributed to remote effects of the cancer. Necessary for signaling by class 3 semaphorins and subsequent remodeling of the cytoskeleton. Plays a role in axon guidance, neuronal growth cone collapse and cell migration. PTM:Phosphorylated upon DNA damage, probably by ATM or ATR. Belongs to the DHOase family. Hydantoinase/dihydropyrimidinase subfamily. subunit:Homotetramer, and heterotetramer with CRMP1, DPYSL2, DPYSL3 or DPYSL5. Interacts with PLEXA1.
- 产品名称Anti-CRMP-3 antibody
- 分子量62 kDa
- 种属反应性Human, Mouse, Rat
- 验证应用WB
- 抗体类型兔多抗
- 免疫原The antiserum was produced against synthesized peptide derived from human DPYSL4. AA range:91-140
- 偶联Non-conjugated
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性能
- 形态Liquid
- 浓度1 mg/mL.
- 存放说明Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles.
- 存储缓冲液Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
- 亚型IgG
- 纯化方式Immunogen affinity purified.
- 其它名称DPYSL4 antibody; CRMP3 antibody; ULIP4 antibody; Dihydropyrimidinase-related protein 4 antibody; DRP-4 antibody; Collapsin response mediator protein 3 antibody; CRMP-3 antibody; UNC33-like phosphoprotein 4 antibody; ULIP-4 antibody;
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Fig1: Western Blot analysis of LOVO cells using CRMP-3 Polyclonal Antibody
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