Anti-CYP3A4/5 antibody
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概述
- 产品描述This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases that catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and its expression is induced by glucocorticoids and some pharmacological agents. This enzyme is involved in the metabolism of approximately half the drugs in use today, including acetaminophen, codeine, cyclosporin A, diazepam and erythromycin. The enzyme also metabolizes some steroids and carcinogens. This gene is part of a cluster of cytochrome P450 genes on chromosome 7q21. 1. Previously another CYP3A gene, CYP3A3, was thought to exist; however, it is now thought that this sequence represents a transcript variant of CYP3A4. Alternatively spliced transcript variants encoding different isofor
- 产品名称Anti-CYP3A4/5 antibody
- 分子量57 kDa
- 种属反应性Human
- 验证应用WB, IHC-P, IF
- 抗体类型兔多抗
- 免疫原The antiserum was produced against synthesized peptide derived from human Cytochrome P450 3A4/5. AA range:251-300
- 偶联Non-conjugated
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性能
- 形态Liquid
- 浓度1 mg/mL.
- 存放说明Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles.
- 存储缓冲液Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
- 亚型IgG
- 纯化方式Immunogen affinity purified.
- 其它名称CYP3A4 antibody; CYP3A3 antibody; Cytochrome P450 3A4 antibody; 1 antibody; 8-cineole 2-exo-monooxygenase antibody; Albendazole monooxygenase antibody; Albendazole sulfoxidase antibody; CYPIIIA3 antibody; CYPIIIA4 antibody; Cytochrome P450 3A3 antibody; Cytochrome P450 HLp antibody; Cytochrome P450 NF-25 antibody; Cytochrome P450-PCN1 antibody; Nifedipine antibody;
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应用
WB: 1:500-1:2000
IHC-P: 1:100-1:300
IF: 1:100-1:500
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Fig1: Western Blot analysis of Jurkat cells using CYP3A4/5 Polyclonal Antibody
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