Anti-MAN1B1 antibody
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概述
- 产品描述This gene encodes an enzyme belonging to the glycosyl hydrolase 47 family. This enzyme functions in N-glycan biosynthesis, and is a class I alpha-1,2-mannosidase that specifically converts Man9GlcNAc to Man8GlcNAc isomer B. It is required for N-glycan trimming to Man5-6GlcNAc2 in the endoplasmic-reticulum-associated degradation pathway. Mutations in this gene cause autosomal-recessive intellectual disability. Alternative splicing results in multiple transcript variants. A related pseudogene has been identified on chromosome 11.
- 产品名称Anti-MAN1B1 antibody
- 分子量80 kDa
- 种属反应性Human
- 验证应用WB
- 抗体类型兔多抗
- 免疫原Synthesized peptide derived from MAN1B1 . at AA range: 100-180
- 偶联Non-conjugated
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性能
- 形态Liquid
- 浓度1 mg/mL.
- 存放说明Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles.
- 存储缓冲液Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
- 亚型IgG
- 纯化方式Immunogen affinity purified.
- 其它名称MAN1B1 antibody; Endoplasmic reticulum mannosyl-oligosaccharide 1 antibody; 2-alpha-mannosidase antibody; ER alpha-1,2-mannosidase antibody; ER mannosidase 1 antibody; ERMan1 antibody; Man9GlcNAc2-specific-processing alpha-mannosidase antibody; Mannosidase alpha class 1B member 1 antibody;
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Fig1: Western Blot analysis of 3T3 cells using MAN1B1 Polyclonal Antibody
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