Anti-N-Shc antibody
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概述
- 产品描述Signaling adapter that couples activated growth factor receptors to signaling pathway in neurons. Involved in the signal transduction pathways of neurotrophin-activated Trk receptors in cortical neurons. PTM:Tyrosine phosphorylated. Contains 1 PID domain. Contains 1 SH2 domain. subunit:Interacts with the Trk receptors in a phosphotyrosine-dependent manner. Once activated, binds to GRB2. Interacts with activated EGF receptors. tissue specificity:Mainly expressed in brain. Hardly detectable in other tissues, except in pancreas. Highly expressed in the cerebral cortex, frontal and temporal lobes, occipital pole, hippocampus, caudate nucleus and amygdala. Expressed at low level in the cerebellum, medulla and spinal cord.
- 产品名称Anti-N-Shc antibody
- 分子量48 kDa
- 种属反应性Human,Mouse,Rat
- 验证应用IHC-P
- 抗体类型兔多抗
- 免疫原The antiserum was produced against synthesized peptide derived from human SHC3. AA range:291-340
- 偶联Non-conjugated
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性能
- 形态Liquid
- 浓度1 mg/mL.
- 存放说明Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles.
- 存储缓冲液Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
- 亚型IgG
- 纯化方式Immunogen affinity purified.
- 其它名称
- SHC3 antibody; NSHC antibody; SHCC antibody; SHC-transforming protein 3 antibody; Neuronal Shc antibody; N-Shc antibody; Protein Rai antibody; SHC-transforming protein C antibody; Src homology 2 domain-containing-transforming protein C3 antibody; SH2 domain protein C3 antibody;
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