Anti-PERK antibody
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概述
- 产品描述The protein encoded by this gene phosphorylates the alpha subunit of eukaryotic translation-initiation factor 2, leading to its inactivation, and thus to a rapid reduction of translational initiation and repression of global protein synthesis. This protein is thought to modulate mitochondrial function. It is a type I membrane protein located in the endoplasmic reticulum (ER), where it is induced by ER stress caused by malfolded proteins. Mutations in this gene are associated with Wolcott-Rallison syndrome.
- 产品名称Anti-PERK antibody
- 分子量125 kDa
- 种属反应性Human,Mouse,Rat
- 验证应用IF,WB,IHC-P
- 抗体类型兔多抗
- 免疫原The antiserum was produced against synthesized peptide derived from human EIF2AK3. AA range:947-996
- 偶联Non-conjugated
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性能
- 形态Liquid
- 浓度1 mg/mL.
- 存放说明Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles.
- 存储缓冲液Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
- 亚型IgG
- 纯化方式Immunogen affinity purified.
- 其它名称
- EIF2AK3 antibody; PEK antibody; PERK antibody; Eukaryotic translation initiation factor 2-alpha kinase 3 antibody; PRKR-like endoplasmic reticulum kinase antibody; Pancreatic eIF2-alpha kinase antibody; HsPEK antibody;
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应用
IF: 1:50-200 WB: 1:500-1:2000
IHC-P: 1:100-1:300
特别提示:本公司的所有产品仅可用于科研实验,严禁用于临床医疗及其他非科研用途!