Anti-RCC2 antibody
-
概述
- 产品描述Required for completion of mitosis and cytokinesis. May function as a guanine nucleotide exchange factor for the small GTPase RAC1. PTM:Phosphorylated upon DNA damage, probably by ATM or ATR. Contains 7 RCC1 repeats. subcellular location:Appears in the nucleus at G2, then concentrates at the inner centromere region of chromosomes during prophase. Redistributes to the midzone of the mitotic spindle during anaphase. Here, the protein covers the entire equatorial diameter from cortex to cortex. subunit:Binds preferentially to the nucleotide-free form of RAC1. Interacts with microtubules.
- 产品名称Anti-RCC2 antibody
- 分子量56 kDa
- 种属反应性Human,Mouse
- 验证应用WB,IHC-P
- 抗体类型兔多抗
- 免疫原The antiserum was produced against synthesized peptide derived from human RCC2. AA range:473-522
- 偶联Non-conjugated
-
性能
- 形态Liquid
- 浓度1 mg/mL.
- 存放说明Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles.
- 存储缓冲液Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
- 亚型IgG
- 纯化方式Immunogen affinity purified.
- 其它名称
- RCC2 antibody; KIAA1470 antibody; TD60 antibody; Protein RCC2 antibody; RCC1-like protein TD-60 antibody; Telophase disk protein of 60 kDa antibody;
-
应用
WB: 1:500-1:2000
IHC-P: 1:100-1:300
特别提示:本公司的所有产品仅可用于科研实验,严禁用于临床医疗及其他非科研用途!