Anti-TCF-4/12 antibody
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概述
- 产品描述This gene encodes transcription factor 4, a basic helix-loop-helix transcription factor. The encoded protein recognizes an Ephrussi-box ('E-box') binding site ('CANNTG') - a motif first identified in immunoglobulin enhancers. This gene is broadly expressed, and may play an important role in nervous system development. Defects in this gene are a cause of Pitt-Hopkins syndrome. In addition, an intronic CTG repeat normally numbering 10-37 repeat units can expand to >50 repeat units and cause Fuchs endothelial corneal dystrophy. Multiple alternatively spliced transcript variants that encode different proteins have been described.
- 产品名称Anti-TCF-4/12 antibody
- 分子量60 kDa
- 种属反应性Human, Mouse, Rat
- 验证应用WB, IHC-P
- 抗体类型兔多抗
- 免疫原The antiserum was produced against synthesized peptide derived from human TCF4/12. AA range:581-630
- 偶联Non-conjugated
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性能
- 形态Liquid
- 浓度1 mg/mL.
- 存放说明Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles.
- 存储缓冲液Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
- 亚型IgG
- 纯化方式Immunogen affinity purified
- 其它名称
- TCF4 antibody; BHLHB19 antibody; ITF2 antibody; SEF2 antibody; Transcription factor 4 antibody; TCF-4 antibody; Class B basic helix-loop-helix protein 19 antibody; bHLHb19 antibody; Immunoglobulin transcription factor 2 antibody; ITF-2 antibody; SL3-3 enhancer factor 2 antibody; SEF-2 antibody; TCF12 antibody; BHLHB20 antibody; HEB antibody; HTF4 antibody; Transcription factor 12 antibody; antibody;
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应用
WB: 1:500-1:2000
IHC-P: 1:100-1:300
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Fig1: Western Blot analysis of various cells using TCF-4/12 Polyclonal Antibody cells nucleus extracted by Minute TM Cytoplasmic and Nuclear Fractionation kit (SC-003,Inventbiotech,MN,USA).
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