Anti-SSX antibody
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概述
- 产品描述The product of this gene belongs to the family of highly homologous synovial sarcoma X (SSX) breakpoint proteins. These proteins may function as transcriptional repressors. They are also capable of eliciting spontaneous humoral and cellular immune responses in cancer patients, and are potentially useful targets in cancer vaccine-based immunotherapy. This gene, and also the SSX2 and SSX4 family members, have been involved in t(X;18)(p11. 2;q11. 2) translocations that are characteristically found in all synovial sarcomas. This translocation results in the fusion of the synovial sarcoma translocation gene on chromosome 18 to one of the SSX genes on chromosome X. The encoded hybrid proteins are likely responsible for transforming activity. Alternative splicing of this gene results in multiple transcript variants. A related pseudogene has been identified on chromosome X.
- 产品名称Anti-SSX antibody
- 分子量25 kDa
- 种属反应性Human
- 验证应用WB, IHC-P
- 抗体类型兔多抗
- 免疫原The antiserum was produced against synthesized peptide derived from the C-terminal region of human SSX1/2/3/4/5/6/7/8/9. AA range:139-188
- 偶联Non-conjugated
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性能
- 形态Liquid
- 浓度1 mg/mL.
- 存放说明Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles.
- 存储缓冲液Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
- 亚型IgG
- 纯化方式Immunogen affinity purified.
- 其它名称
- SSX1 antibody; Protein SSX1 antibody; Cancer/testis antigen 5.1 antibody; CT5.1 antibody; Synovial sarcoma, X breakpoint 1 antibody; SSX2 antibody; SSX2A antibody; SSX2B antibody; Protein SSX2 antibody; Cancer/testis antigen 5.2 antibody; CT5.2 antibody; Synovial sarcoma, X breakpoint 2 antibody; Tumor antigen HOM-MEL-40 antibody; SSX3 antibody; Protein SSX3 antibody;Cancer/testis antigen 5.3 antibody; CT5.3 antibody; SSX4 antibody; SSX4A antibody; SSX4B antibody; Protein SSX4 antibody; Cancer/testis antigen 5.4 antibody; CT5.4 antibody; SSX5 antibody; Protein SSX5 antibody; SSX6 antibody; Putative protein SSX6 antibody; SSX7 antibody; Protein SSX7 antibody; SSX8 antibody; Protein SSX8 antibody; SSX9 antibody; Protein SSX9 antibody;
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应用
WB: 1:500-1:2000
IHC-P: 1:100-300
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Fig1: Western Blot analysis of 22RV-1, SW480 cells using SSX Polyclonal Antibody.. Secondary antibody（catalog#：HA1001) was diluted at 1:20000
Fig2: Immunohistochemical analysis of paraffin-embedded human-skin, antibody was diluted at 1:100
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