Anti-Siglec-5/14 antibody
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概述
- 产品描述This gene encodes a member of the sialic acid-binding immunoglobulin-like lectin (Siglec) family. These cell surface lectins are characterized by structural motifs in the immunoglobulin (Ig)-like domains and sialic acid recognition sites in the first Ig V set domain. The encoded protein is a member of the CD33-related subset of Siglecs and inhibits the activation of several cell types including monocytes, macrophages and neutrophils. Binding of group B Streptococcus (GBS) to the encoded protein plays a role in GBS immune evasion.
- 产品名称Anti-Siglec-5/14 antibody
- 分子量60 kDa
- 种属反应性Human
- 验证应用WB, IHC-P
- 抗体类型兔多抗
- 免疫原Synthesized peptide derived from Sialic acid-binding Ig-like lectin 5/Sialic acid-binding Ig-like lectin 14 at AA range: 91-140
- 偶联Non-conjugated
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性能
- 形态Liquid
- 浓度1 mg/mL.
- 存放说明Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles.
- 存储缓冲液Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
- 亚型IgG
- 纯化方式Immunogen affinity purified.
- 其它名称
- SIGLEC5 antibody; CD33L2 antibody; OBBP2 antibody; Sialic acid-binding Ig-like lectin 5 antibody; Siglec-5 antibody; CD33 antigen-like 2 antibody; Obesity-binding protein 2 antibody; OB-BP2 antibody; OB-binding protein 2 antibody; CD170 antibody; SIGLEC14 antibody; Sialic acid-binding Ig-like lectin 14 antibody; Siglec-14 antibody;
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应用
WB: 1:500-1:2000
IHC-P: 1:100-300
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Fig1: Western Blot analysis of L929 cells using Siglec-5/14 Polyclonal Antibody. Antibody was diluted at 1:1000. Secondary antibody（catalog#：HA1001) was diluted at 1:20000
Fig2: Immunohistochemical analysis of paraffin-embedded human-spleen, antibody was diluted at 1:100
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