Anti-LIR-1 antibody
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概述
- 产品描述This gene is a member of the leukocyte immunoglobulin-like receptor (LIR) family, which is found in a gene cluster at chromosomal region 19q13. 4. The encoded protein belongs to the subfamily B class of LIR receptors which contain two or four extracellular immunoglobulin domains, a transmembrane domain, and two to four cytoplasmic immunoreceptor tyrosine-based inhibitory motifs (ITIMs). The receptor is expressed on immune cells where it binds to MHC class I molecules on antigen-presenting cells and transduces a negative signal that inhibits stimulation of an immune response. It is thought to control inflammatory responses and cytotoxicity to help focus the immune response and limit autoreactivity. Multiple transcript variants encoding different isoforms have been found for this gene.
- 产品名称Anti-LIR-1 antibody
- 分子量72 kDa
- 种属反应性Human
- 验证应用WB
- 抗体类型兔多抗
- 免疫原The antiserum was produced against synthesized peptide derived from the N-terminal region of human LILRB1. AA range:21-70
- 偶联Non-conjugated
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性能
- 形态Liquid
- 浓度1 mg/mL.
- 存放说明Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles.
- 存储缓冲液Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
- 亚型IgG
- 纯化方式Immunogen affinity purified.
- 其它名称
- LILRB1 antibody; ILT2 antibody; LIR1 antibody; MIR7 antibody; Leukocyte immunoglobulin-like receptor subfamily B member 1 antibody; LIR-1 antibody; Leukocyte immunoglobulin-like receptor 1 antibody; CD85 antigen-like family member J antibody; Immunoglobulin-like transcript 2 antibody; ILT-2 antibody; Monocyte/macrophage immunoglobulin-like receptor 7 antibody; MIR-7 antibody; CD85j antibody;
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Fig1: Western Blot analysis of SKOV3 cells using LIR-1 Polyclonal Antibody.. Secondary antibody（catalog#：HA1001) was diluted at 1:20000
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