Anti-TIRAP antibody
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概述
- 产品描述The innate immune system recognizes microbial pathogens through Toll-like receptors (TLRs), which identify pathogen-associated molecular patterns. Different TLRs recognize different pathogen-associated molecular patterns and all TLRs have a Toll-interleukin 1 receptor (TIR) domain, which is responsible for signal transduction. The protein encoded by this gene is a TIR adaptor protein involved in the TLR4 signaling pathway of the immune system. It activates NF-kappa-B, MAPK1, MAPK3 and JNK, which then results in cytokine secretion and the inflammatory response. Alternative splicing of this gene results in several transcript variants; however, not all variants have been fully described.
- 产品名称Anti-TIRAP antibody
- 种属反应性Human, Mouse
- 验证应用IHC-P, WB
- 抗体类型兔多抗
- 免疫原The antiserum was produced against synthesized peptide derived from human TIRAP. AA range:52-101
- 偶联Non-conjugated
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性能
- 形态Liquid
- 浓度1 mg/mL.
- 存放说明Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles.
- 存储缓冲液Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
- 亚型IgG
- 纯化方式Immunogen affinity purified.
- 其它名称
- TIRAP antibody; MAL antibody; Toll/interleukin-1 receptor domain-containing adapter protein antibody; TIR domain-containing adapter protein antibody; Adaptor protein Wyatt antibody; MyD88 adapter-like protein antibody;
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应用
WB: 1:500-1:2000
IHC-P: 1:100-1:300
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Fig1: Immunohistochemical analysis of paraffin-embedded Human brain. Antibody was diluted at 1:100(4°,overnight). High-pressure and temperature Tris-EDTA,pH8.0 was used for antigen retrieval. Negetive contrl (right) obtaned from antibody was pre-absorbed by immunogen peptide.
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