Anti-SPTLC1 antibody
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概述
- 产品描述This gene encodes a member of the class-II pyridoxal-phosphate-dependent aminotransferase family. The encoded protein is the long chain base subunit 1 of serine palmitoyltransferase. Serine palmitoyltransferase converts L-serine and palmitoyl-CoA to 3-oxosphinganine with pyridoxal 5'-phosphate and is the key enzyme in sphingolipid biosynthesis. Mutations in this gene were identified in patients with hereditary sensory neuropathy type 1. Alternatively spliced variants encoding different isoforms have been identified. Pseudogenes of this gene have been defined on chromosomes 1, 6, 10, and 13.
- 产品名称Anti-SPTLC1 antibody
- 分子量52 kDa
- 种属反应性Human, Mouse, Rat
- 验证应用WB, IHC-P
- 抗体类型兔多抗
- 免疫原Synthesized peptide derived from SPTLC1 . at AA range: 411-460
- 偶联Non-conjugated
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性能
- 形态Liquid
- 浓度1 mg/mL.
- 存放说明Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles.
- 存储缓冲液Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
- 亚型IgG
- 纯化方式Immunogen affinity purified.
- 其它名称
- SPTLC1 antibody; LCB1 antibody; Serine palmitoyltransferase 1 antibody; Long chain base biosynthesis protein 1 antibody; LCB 1 antibody; Serine-palmitoyl-CoA transferase 1 antibody; SPT 1 antibody; SPT1 antibody;
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应用
WB: 1:500-1:2000
IHC-P: 1:100-300
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Fig1: Western Blot analysis of HepG2 cells using SPTLC1 Polyclonal Antibody. Antibody was diluted at 1:500. Secondary antibody（catalog#：HA1001) was diluted at 1:20000
Fig2: Immunohistochemical analysis of paraffin-embedded rat-brain, antibody was diluted at 1:100
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