Anti-MCM6 antibody
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概述
- 产品描述The protein encoded by this gene is one of the highly conserved mini-chromosome maintenance proteins (MCM) that are essential for the initiation of eukaryotic genome replication. The hexameric protein complex formed by the MCM proteins is a key component of the pre-replication complex (pre_RC) and may be involved in the formation of replication forks and in the recruitment of other DNA replication related proteins. The MCM complex consisting of this protein and MCM2, 4 and 7 proteins possesses DNA helicase activity, and may act as a DNA unwinding enzyme. The phosphorylation of the complex by CDC2 kinase reduces the helicase activity, suggesting a role in the regulation of DNA replication. Single nucleotide polymorphisms in the intron regions of this gene are associated with differential transcriptional activation of the promoter of the neighboring lactase gene and, thereby, i
- 产品名称Anti-MCM6 antibody
- 分子量90 kDa
- 种属反应性Human, Mouse, Rat
- 验证应用WB
- 抗体类型兔多抗
- 免疫原The antiserum was produced against synthesized peptide derived from the Internal region of human MCM6. AA range:331-380
- 偶联Non-conjugated
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性能
- 形态Liquid
- 浓度1 mg/mL.
- 存放说明Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles.
- 存储缓冲液Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
- 亚型IgG
- 纯化方式Immunogen affinity purified.
- 其它名称
- MCM6 antibody; DNA replication licensing factor MCM6 antibody; p105MCM antibody;
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Fig1: Western Blot analysis of HeLa cells using MCM6 Polyclonal Antibody .. Secondary antibody(catalog#:HA1001) was diluted at 1:20000 cells nucleus extracted by Minute TM Cytoplasmic and Nuclear Fractionation kit (SC-003,Inventbiotech,MN,USA).
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