Anti-MYBPC3 antibody
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概述
- 产品描述MYBPC3 encodes the cardiac isoform of myosin-binding protein C. Myosin-binding protein C is a myosin-associated protein found in the cross-bridge-bearing zone (C region) of A bands in striated muscle. MYBPC3, the cardiac isoform, is expressed exclussively in heart muscle. Regulatory phosphorylation of the cardiac isoform in vivo by cAMP-dependent protein kinase (PKA) upon adrenergic stimulation may be linked to modulation of cardiac contraction. Mutations in MYBPC3 are one cause of familial hypertrophic cardiomyopathy.
- 产品名称Anti-MYBPC3 antibody
- 分子量140 kDa
- 种属反应性Human, Mouse, Rat
- 验证应用WB
- 抗体类型兔多抗
- 免疫原Synthesized peptide derived from human MYBPC3 Polyclonal
- 偶联Non-conjugated
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性能
- 形态Liquid
- 浓度1 mg/mL.
- 存放说明Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles.
- 存储缓冲液Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
- 亚型IgG
- 纯化方式Immunogen affinity purified.
- 其它名称
- Myosin-binding protein C, cardiac-type (Cardiac MyBP-C) (C-protein, cardiac muscle isoform) antibody;
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Fig1: Western blot analysis of mouse-kidney lysate, antibody was diluted at 1000. Secondary antibody(catalog#:HA1001) was diluted at 1:20000
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