Anti-Apolipoprotein A1 antibody
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概述
- 产品描述Apolipoproteins are protein components of plasma lipoproteins. The human apoA-I gene encodes a single chain, 243 amino acid protein which promotes cholesterol efflux from tissues to the liver for excretion. ApoA-I is the major protein component of high density lipoprotein (HDL) in the plasma. ApoA-I can function as a cofactor for lecithin cholesterolacyltransferase (LCAT), which is responsible for the formation of most plasma cholesteryl esters. The human apoA-II gene encodes the second most abundant protein of HDL particles, where it influences plasma levels of free fatty acids. The human apoA-IV gene encodes a 396 amino acid preprotein, which after proteolytic processing is secreted from the intestine in association with chylomicron particles. ApoA-IV is a potent activator of LCAT in vitro. The human apoA-V gene encodes a 366 amino acid protein that is believed to be an important determinant of plasma triglyceride levels.
- 产品名称Anti-Apolipoprotein A1 antibody
- 分子量28 kDa
- 种属反应性Human,Mouse,Rat
- 验证应用WB,IP,IF
- 抗体类型兔多抗
- 免疫原peptide
- 偶联Non-conjugated
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性能
- 形态Liquid
- 浓度1 mg/mL.
- 存放说明Store at +4℃
- 存储缓冲液1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.
- 亚型IgG
- 纯化方式Immunogen affinity purified
- 亚细胞定位Secreted
- 其它名称
- Apo-AI antibody
- ApoA I antibody
- ApoA-I antibody
more
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应用
WB: 1:100-1,000
IP: 1-2 ug per 100-500 ug of total protein (1ml of cell lysate)
IF: 1:50-1:500
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Fig1: Western blot analysis of apoA-I expression from purified human VLDL (A) and HDL (B).
Fig2: Western blot analysis of apoA-I expression in non-transfected (A) and mouse apoA-Itransfected (B) 293T whole cell lysates.
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