Anti-YARS2 antibody
-
概述
- 产品描述Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr). Defects in YARS2 are the cause of myopathy with lactic acidosis and sideroblastic anemia type 2 (MLASA2) [MIM:613561]. MLASA2 is a rare oxidative phosphorylation disorder specific to skeletal muscle and bone marrow. Affected individuals manifest sideroblastic anemia, progressive lethargy, muscle weakness, and exercise intolerance associated with persistent lactic acidemia.
- 产品名称Anti-YARS2 antibody
- 分子量53 kDa
- 种属反应性Zebrafish
- 验证应用IF, IHC-P
- 抗体类型兔多抗
- 免疫原Recombinant protein within Zebrafish YARS2 aa 271-494.
- 偶联Non-conjugated
-
性能
- 形态Liquid
- 浓度1 mg/mL.
- 存放说明Store at +4℃ after thawing. Aliquot store at -20℃. Avoid repeated freeze / thaw cycles.
- 存储缓冲液1*PBS (pH7.4), 0.2% BSA, 50% Glycerol. Preservative: 0.05% Sodium Azide.
- 亚型IgG
- 纯化方式Protein affinity purified.
- 亚细胞定位Cytosol. Mitochondrion.
- 其它名称
- CGI 04 antibody
- FLJ13995 antibody
- mitochondrial antibody
more
-
应用
IF:1:50-1:200
IHC-P:1:50-1:200
-
Fig1: IF staining of YARS2 in Zebrafish embryos (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.
Fig2: Immunohistochemical analysis of paraffin-embedded Zebrafish embryos tissue section using anti-YARS2 antibody. Counter stained with hematoxylin.
特别提示：本公司的所有产品仅可用于科研实验，严禁用于临床医疗及其他非科研用途！
