Anti-AVPR1A antibody

Anti-AVPR1A antibody

• 概述

• 产品描述Human AVPR1A cDNA is 1472 bp long and encodes a 418 amino-acid long polypeptide which shares 72%, 36%, 37%, and 45% sequence identity with rat Avpr1a, human AVPR2, rat Avpr2, and human oxytocin receptor (OXTR), respectively. AVPR1A is a G-protein coupled receptor (GPCR) with 7 transmembrane domains that couples to Gaq/11 GTP binding proteins, which along with Gbl, activate phospholipase C activity.[5][6] Clinically, the V1A receptor is related to vasoconstriction compared to the V1B receptor that is more related to ACTH release or the V2 receptor that is linked to the diuretic function of ADH.
• 产品名称Anti-AVPR1A antibody
• 分子量Predicted band size: 47 kDa.
• 种属反应性Human,Mouse
• 验证应用WB
• 抗体类型兔多抗
• 免疫原Synthetic peptide within N-terminal human AVPR1A.

• 性能

• 形态Liquid
• 浓度1 mg/mL.
• 存放说明Store at +4℃ after thawing. Aliquot store at -20℃. Avoid repeated freeze / thaw cycles.
• 存储缓冲液1*TBS (pH7.4), 0.2% BSA, 50% Glycerol. Preservative: 0.05% Sodium Azide.
• 纯化方式Peptide affinity purified.
• 亚细胞定位Cell membrane, Membrane.
• 其它名称
  • Antidiuretic hormone receptor 1a antibody
  • Arginine vasopressin receptor 1A antibody
  • AVPR 1 antibody
  more

• 应用

  WB: 1:500-1:1,000

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  Fig1: Western blot analysis of AVPR1A on different lysates. Proteins were transferred to a PVDF membrane and blocked with 5% BSA in PBS for 1 hour at room temperature. The primary antibody was used in 5% BSA at room temperature for 2 hours. Goat Anti-Rabbit IgG - HRP Secondary Antibody (HA1001) at 1:5,000 dilution was used for 1 hour at room temperature.
  Positive control:
  Lane 1: A549 cell lysate
  Lane 2: HL-60 cell lysate
  Lane 3: C2C12 cell lysate
  Lane 4: Mouse liver tissue lysate

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