Anti-CTHRC1 antibody [5H1]

Anti-CTHRC1 antibody [5H1]

• 概述

• 产品描述CTHRC1 (collagen triple helix repeat containing 1) is a 243 amino acid secreted protein that localizes to the extracellular matrix and contains one collagen-like domain. Expressed as two alternatively spliced isoforms, the first of which is expressed in calcified atherosclerotic plaque and chondrocyte-like cells, CTHRC1 is thought to function as a negative regulator of collagen matrix deposition and may also play a role in the stabilization of ligand-receptor interactions in the Wnt pathway. CTHRC1 is widely present in a variety of cancers, including melanoma and breast carcinoma, and may participate in cancer cell migration and cancer tissue invasion and metastasis. The gene encoding CTHRC1 maps to human chromosome 8, which consists of nearly 146 million base pairs, houses more than 800 genes and is associated with a variety of diseases and malignancies.
• 产品名称Anti-CTHRC1 antibody [5H1]
• 分子量26 kDa
• 种属反应性Human,Mouse,Rat
• 验证应用WB,IHC-P
• 抗体类型小鼠单抗
• 免疫原Recombinant protein
• 偶联Non-conjugated

• 性能

• 形态Liquid
• 浓度2 mg/mL.
• 存放说明Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles.
• 存储缓冲液1*PBS (pH7.4), 0.2% BSA, 50% Glycerol. Preservative: 0.05% Sodium Azide.
• 亚型IgG1
• 纯化方式Protein A purified.
• 亚细胞定位Extracellular matrix. Secreted.
• 其它名称
  • Collagen triple helix repeat containing 1 antibody
  • Collagen triple helix repeat containing protein 1 antibody
  • Collagen triple helix repeat-containing protein 1 antibody
  more

• 应用

  WB: 1:500-1:1,000
  IHC-P: 1:50-1:200

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  Fig1: Western blot analysis of CTHRC1 on CTHRC1 recombinant protein using anti-CTHRC1 antibody at 1/500 dilution.

   

  

  Fig2: Immunohistochemical analysis of paraffin-embedded human kidney tissue using anti-CTHRC1 antibody. Counter stained with hematoxylin.

   

  

  Fig3: Immunohistochemical analysis of paraffin-embedded human placenta tissue using anti-CTHRC1 antibody. Counter stained with hematoxylin.

   

  

  Fig4: Immunohistochemical analysis of paraffin-embedded rat large intestine tissue using anti-CTHRC1 antibody. Counter stained with hematoxylin.

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