Anti-IL18 antibody [AH16-10]

Anti-IL18 antibody [AH16-10]

• 概述

• 产品描述Interleukin-18 (IL-18) has been identified as a molecule that induces IFN-g production and enhances NK cell cytotoxicity. IL-18 receptor (IL-18R) is a type I membrane protein present in lung, leukocytes, spleen, liver, thymus, prostate, small intestine, colon, placenta and heart, absent from brain, skeletal muscle, pancreas and kidney. IL-18R is present in Hodgkin's disease cell lines, and does not bind IL-1α or IL-1β. The association of IL-18 to IL-18R leads to activation of NFκB. At present two subunits of IL-18R have been characterized: IL-18Rα and IL-18Rβ. IL-18Rα has been described as the ligand-binding chain and IL-18Rβ as the signal-transduction chain.
• 产品名称Anti-IL18 antibody [AH16-10]
• 分子量22 kDa
• 种属反应性Human,Mouse
• 验证应用ICC,IHC-P,WB,ELISA(Cap)
• 抗体类型小鼠单抗
• 免疫原recombinant protein
• 偶联Non-conjugated

• 性能

• 形态Liquid
• 浓度2 mg/mL.
• 存放说明Store at -20 ℃. Stable for 12 months from date of receipt.
• 存储缓冲液1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.07% Sodium Azide.
• 亚型IgG1
• 亚细胞定位Secreted.
• 其它名称
  • Iboctadekin antibody
  • IFN gamma inducing factor antibody
  • IFN-gamma-inducing factor antibody
  more

• 应用

  WB: 1:1,000
  ICC: 1:50-1:200
  IHC-P: 1:50-1:200
  ELISA: 1:5,000-1:10,000

•  

  

  Fig1: ICC staining IL18 in A431 cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.

   

  

  Fig2: ICC staining IL18 in Hela cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.

   

  

  Fig3: ICC staining IL18 in PC-12 cells (green). The nuclear counter stain is DAPI (blue).Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.

   

  

  Fig4: Immunohistochemical analysis of paraffin-embedded human spleen tissue using anti-IL18 antibody. Counter stained with hematoxylin.

   

  

  Fig5: Immunohistochemical analysis of paraffin-embedded mouse spleen tissue using anti-IL18 antibody. Counter stained with hematoxylin.

   

  

  Fig6: Immunohistochemical analysis of paraffin-embedded human tonsil tissue using anti-IL18 antibody. Counter stained with hematoxylin.

特别提示：本公司的所有产品仅可用于科研实验，严禁用于临床医疗及其他非科研用途！