Anti-kinase D-interacting substrate 220 antibody [3-B6]

Anti-kinase D-interacting substrate 220 antibody [3-B6] 

• 概述

• 产品描述Kinase D-interacting substrate 220 (Kidins220), also known as ARMS (ankyrin-rich membrane spanning) is an integral plasma membrane protein predominantly expressed in brain and neurons that presents a polarized location in neural cells, concentrating at the tip of extending neurites and in plasma membrane micro-domains corresponding to lipid rafts. The primary amino acid sequence of Kidins220 reveals 11 ankyrin repeats, 4 trans-membrane domains, a proline-rich region, a sterile-α motif (or SAM) domain, and a type I postsynaptic density-95/discs large/zonula occludens-1 (PDZ)-binding motif at the very C-terminus.
• 产品名称Anti-kinase D-interacting substrate 220 antibody [3-B6]
• 分子量199kDa
• 种属反应性Mouse,Human
• 验证应用WB, ICC, IHC-P
• 抗体类型小鼠单抗
• 免疫原protein
• 偶联Non-conjugated

• 性能

• 形态Liquid
• 浓度2 mg/mL.
• 存放说明Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles.
• 存储缓冲液1*PBS (pH7.4), 0.2% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
• 亚型IgG1
• 纯化方式Protein A purified.
• 亚细胞定位Cell membrane

• 应用

  WB: 1:1,000-1:10,000
  ICC: 1:100
  IHC-P: 1:50

•  

  

  Fig1: Western blot analysis on recombinant protein using anti-Kidins220 Mouse mAb (Cat. # M0910-4).

   

  

  Fig2: Immunofluorescent staining of F9 cells using anti-Kidins220 Mouse mAb (Cat. # M0910-4).

   

  

  Fig3: Immunohistochemical analysis of paraffin- embedded mouse brain tissue using anti-Kidins220 Mouse mAb (Cat. # M0910-4).

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