Anti-FOXF2 antibody [3G1]

Anti-FOXF2 antibody [3G1]

• 概述

• 产品描述The FOX family of transcription factors share a common DIUA binding domain termed a winged-helix or forkhead domain. Many FOX proteins play important roles in development, metabolism, cancer and aging. Development of the vertebrate gut is controlled by paracrine crosstalk between the endodermal epithelium and the associated splanchnic mesoderm. FOXF2 (forkhead box F2), also known as FKHL or FREAC2, is expressed in lung and placenta, and has been shown to transcriptionally activate several lung-specific genes. FOXF2 interacts with transcription factors TFIIB and TBP, and may be involved in regulating transcription in embryogenesis and pattern formation in multicellular organisms. FOXF2-deficient mice develop cleft palate and an abnormal tongue, which suggests that FOXF2 may be critical for palatogenesis.
• 产品名称Anti-FOXF2 antibody [3G1]
• 分子量40 kDa
• 种属反应性Human,Mouse
• 验证应用WB,IP,IF
• 抗体类型小鼠单抗
• 免疫原Recombinant FOXF2 of human origin.
• 偶联Non-conjugated

• 性能

• 形态Liquid
• 浓度2 mg/mL.
• 存放说明Store at +4℃
• 存储缓冲液1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.
• 亚型IgG1
• 纯化方式Protein A purified.
• 亚细胞定位Nucleus
• 其它名称
  • FKH L6 antibody
  • FKHL 6 antibody
  • FKHL6 antibody
  more

• 应用

  WB: 1:100-1:1,000
  IP: 1-2 μg per 100-500 μg of total protein(1 ml of cell lysate) IF 1:50-500

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  Fig1: Western blot analysis of FOXF2 expression in HepG2 (A), HeLa (B), A549 (C) and THP-1 (D) nuclear extracts.

   

  

  Fig2: Immunofluorescence staining of paraformaldehyde-fixed HeLa cells showing nuclear localization.

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