Anti-Rab10 antibody [F8-E2]

Anti-Rab10 antibody [F8-E2]

• 概述

• 产品描述The Ras-related superfamily of guanine nucleotide binding proteins, which includes the Ral / Rec, Rap, R-Ras, and Rho / Rab subfamilies, exhibit 30-60% homology with Ras p21. Accumulating data suggests an important role for Rab proteins, either in endocytosis or in biosynthetic protein transport. The transport of newly synthesized proteins from the endoplasmic reticulum to various stacks of the Golgi complex and to secretory vesicles involves at each stage the movement of carrier vesicles, a process that appears to involve Rab protein function. The possibility that Rab proteins might also direct the exocytosis from secretory vesicles to the plasma membrane is supported by the observation that in yeast, the SEC4 protein, which is 40% homologous to Rab proteins, is associated with secretory vesicles. Several members of the Rab subfamily have been identified, each of which is found at a particular stage of a membrane transport pathway.
• 产品名称Anti-Rab10 antibody [F8-E2]
• 分子量23 kDa
• 种属反应性Human,Mouse
• 验证应用WB,ICC
• 抗体类型小鼠单抗
• 免疫原Recombinant protein
• 偶联Non-conjugated

• 性能

• 形态Liquid
• 浓度2 mg/mL.
• 存放说明Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles.
• 存储缓冲液1*TBS (pH7.4), 1%BSA, Preservative: 0.05% Sodium Azide.
• 亚型IgG1
• 纯化方式Protein A purified.
• 亚细胞定位Cytoplasmic vesicle membrane. Cytosol.
• 其它名称
  • GTP binding protein RAB10 antibody
  • Rab10 antibody
  • RAB10 member RAS oncogene family antibody
  more

• 应用

  WB: 1:500-1:1,000
  ICC: 1:50-1:200

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  Fig1: Western blot analysis of Rab10 on Hela (1) and NIH/3T3 (2) cell lysate using anti-Rab10 antibody at 1/1,000 dilution.

   

  

  Fig2: ICC staining Rab10 (green) in LOVO cells. The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.

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