Anti-KHSRP antibody [A7-B0]

Anti-KHSRP antibody [A7-B0] 

• 概述

• 产品描述Binds to the dendritic targeting element and may play a role in mRNA trafficking. Part of a ternary complex that binds to the downstream control sequence (DCS) of the pre-mRNA. Mediates exon inclusion in transcripts that are subject to tissue-specific alternative splicing. May interact with single-stranded DNA from the far-upstream element (FUSE). May activate gene expression. Also involved in degradation of inherently unstable mRNAs that contain AU-rich elements (AREs) in their 3'-UTR, possibly by recruiting degradation machinery to ARE-containing mRNAs.
• 产品名称Anti-KHSRP antibody [A7-B0]
• 分子量73 kDa
• 种属反应性Human,Mouse,Rat
• 验证应用WB,FC
• 抗体类型小鼠单抗
• 免疫原Synthetic peptide within human KHSRP aa 600-700.
• 偶联Non-conjugated

• 性能

• 形态Liquid
• 浓度2 mg/mL.
• 存放说明Store at +4℃ after thawing. Aliquot store at -20℃. Avoid repeated freeze / thaw cycles.
• 存储缓冲液1*PBS (pH7.4), 0.2% BSA, 50% Glycerol. Preservative: 0.05% Sodium Azide.
• 亚型IgM
• 纯化方式ProG purified.
• 亚细胞定位Nucleus.
• 其它名称
  • Far upstream element-binding protein 2 antibody
  • FBP2 antibody
  • FUBP2 antibody
  more

• 应用

  WB: 1:500-1:2,000
  FC: 1:50-1:100

•  

  

  Fig1: Western blot analysis of KHSRP on Jurkat cell lysate using anti-KHSRP antibody at 1/500 dilution.

   

  

  Fig2: Flow cytometric analysis of HT-29 cells with KHSRP antibody at 1/100 dilution (red) compared with an unlabelled control (cells without incubation with primary antibody; black). Alexa Fluor 488-conjugated goat anti-mouse IgG was used as the secondary antibody.

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