Anti-14-3-3 b/a antibody [9-26]

Anti-14-3-3 b/a antibody [9-26]

• 概述

• 产品描述The 14-3-3 proteins are a family of proteins involved in the regulation of apoptosis, mitogenic signaling and cell-cycle checkpoints. The 14-3-3 proteins are thought to be key regulators of signal transduction events mediated through their binding to serine-phosphorylated proteins. Through binding Bad, 14-3-3 prevents apoptosis by sequestering Bad to the cytosol. The 14-3-3 proteins are also Adapter protein implicated in the regulation of a large spectrum of both general and specialized signaling pathway. They bind to a large number of partners, usually by recognition of a phosphoserine or phosphothreonine motif. Binding generally results in the modulation of the activity of the binding partner.
• 产品名称Anti-14-3-3 b/a antibody [9-26]
• 分子量28 kDa
• 种属反应性Human,Mouse,Rat,Zebrafish
• 验证应用WB,ICC,IHC-P
• 抗体类型小鼠单抗
• 免疫原peptide
• 偶联Non-conjugated

• 性能

• 形态Liquid
• 浓度2 mg/mL.
• 存放说明Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles.
• 存储缓冲液1*PBS (pH7.4), 0.2% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
• 亚型IgG2a
• 纯化方式Protein A purified.
• 亚细胞定位Cytoplasm
• 其它名称
  • 14 3 3 alpha antibody
  • 14 3 3 protein beta/alpha antibody
  • 14-3-3 protein beta/alpha antibody
  more

• 应用

  WB: 1:1,000-1:2,000
  ICC: 1:100
  IHC-P: 1:200

•  

  

  Fig1: Western blot analysis on mouse liver lysates using anti-14-3-3b/a Mouse mAb (Cat. # M0407-14).

   

  

  Fig2: Immunofluorescent staining of Hela cells using anti-14-3-3b/a Mouse mAb (Cat. # M0407-14).

   

  

  Fig3: Immunohistochemical analysis of paraffin- embedded human breast carcinoma tissue using anti-14-3-3b/a Mouse mAb (Cat. # M0407-14).

   

  

  Fig4: Western blot analysis of 14-3-3b/a on hybrid fish (crucian-carp) brain tissue lysate using anti-14-3-3b/a antibody at 1/500 dilution.

   

  

  Fig5: Immunohistochemical analysis of paraffin-embedded Zebrafish tissue using anti-14-3-3b/a antibody. Counter stained with hematoxylin.

特别提示：本公司的所有产品仅可用于科研实验，严禁用于临床医疗及其他非科研用途！