Anti-c-FOS antibody [A10-G2]
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概述
- 产品描述The Fos gene family consists of 4 members: FOS, FOSB, FOSL1, and FOSL2. These genes encode leucine zipper proteins that can dimerize with proteins of the JUN family, thereby forming the transcription factor complex AP-1. As such, the FOS proteins have been implicated as regulators of cell proliferation, differentiation, and transformation. In some cases, expression of the FOS gene has also been associated with apoptotic cell death.
- 产品名称Anti-c-FOS antibody [A10-G2]
- 分子量41 kDa
- 种属反应性Human
- 验证应用WB,IHC-P,FC
- 抗体类型小鼠单抗
- 免疫原Recombinant protein
- 偶联Non-conjugated
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性能
- 形态Liquid
- 浓度2 mg/mL.
- 存放说明Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles.
- 存储缓冲液1*TBS (pH7.4), 1%BSA, Preservative: 0.05% Sodium Azide.
- 亚型IgG1
- 纯化方式Protein A purified.
- 亚细胞定位Cytosol, Nucleus.
- 其它名称
- Activator protein 1 antibody
- AP 1 antibody
- C FOS antibody
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应用
WB: 1:500-1:1,000
IHC-P: 1:50-1:200
FC: 1:100-1:200
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Fig1: Western blot analysis of c-FOS on human c-FOS recombinant protein using anti-c-FOS antibody at 1/1,000 dilution.
Fig2: Western blot analysis of c-FOS on HeLa (1) and HeLa (2) cell lysate using anti-c-FOS antibody at 1/1,000 dilution.
Fig3: Immunohistochemical analysis of paraffin-embedded human colon cancer tissue using anti-c-FOS antibody. Counter stained with hematoxylin.
Fig4: Immunohistochemical analysis of paraffin-embedded human cerebellum tissue using anti-c-FOS antibody. Counter stained with hematoxylin.
Fig5: Flow cytometric analysis of HeLa cells with c-FOS antibody at 1/100 dilution (green) compared with an unlabelled control (cells without incubation with primary antibody; red).
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