Anti-IL1RAPL1 antibody

Anti-IL1RAPL1 antibody

• 概述

• 产品描述May regulate secretion and presynaptic differentiation through inhibition of the activity of N-type voltage-gated calcium channel. May activate the MAP kinase JNK. The protein encoded by this gene is a member of the interleukin 1 receptor family and is similar to the interleukin 1 accessory proteins. It is most closely related to interleukin 1 receptor accessory protein-like 2 (IL1RAPL2). This gene and IL1RAPL2 are located at a region on chromosome X that is associated with X-linked non-syndromic mental retardation. Deletions and mutations in this gene were found in patients with mental retardation. This gene is expressed at a high level in post-natal brain structures involved in the hippocampal memory system, which suggests a specialized role in the physiological processes underlying memory and learning abilities.
• 产品名称Anti-IL1RAPL1 antibody
• 分子量80 kDa
• 种属反应性Human
• 验证应用WB,ICC,FC
• 抗体类型小鼠单抗
• 免疫原Recombinant protein
• 偶联Non-conjugated

• 性能

• 形态Liquid
• 浓度2 mg/mL.
• 存放说明Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles.
• 存储缓冲液1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.
• 亚型IgG1
• 纯化方式Protein A purified.
• 亚细胞定位Cell membrane. Cytoplasm.
• 其它名称
  • IL 1 RAPL 1 antibody
  • IL 1RAPL 1 antibody
  • IL-1-RAPL-1 antibody
  more

• 应用

  WB: 1:500-1:2,000
  ICC: 1:50-1:200
  FC: 1:100-1:200

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  Fig1: Western blot analysis of IL1RAPL1 on human IL1RAPL1 recombinant protein using anti-IL1RAPL1 antibody at 1/1,000 dilution.

   

  

  Fig2: Western blot analysis of IL1RAPL1 on HEK293 (1) and IL1RAPL1-hIgGFc transfected HEK293 (2) cell lysate using anti-IL1RAPL1 antibody at 1/1,000 dilution.

   

  

  Fig3: Western blot analysis of IL1RAPL1 on different cell lysate using anti-IL1RAPL1 antibody at 1/1,000 dilution.
  Positive control:
  Lane 1: A431
  Lane 2: SK-Hep-1
  Lane 3: HL-7702

   

  

  Fig4: ICC staining IL1RAPL1 (green) and Actin filaments (red) in Hela cells. The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.

   

  

  Fig5: Flow cytometric analysis of Hela cells with IL1RAPL1 antibody at 1/100 dilution (green) compared with an unlabelled control (cells without incubation with primary antibody; red).

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