Anti-CBX3 antibody
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概述
- 产品描述Seems to be involved in transcriptional silencing in heterochromatin-like complexes. Recognizes and binds histone H3 tails methylated at 'Lys-9', leading to epigenetic repression. May contribute to the association of the heterochromatin with the inner nuclear membrane through its interaction with lamin B receptor (LBR). Involved in the formation of functional kinetochore through interaction with MIS12 complex proteins.
- 产品名称Anti-CBX3 antibody
- 分子量21 kDa
- 种属反应性Human
- 验证应用WB,IHC-P,FC
- 抗体类型小鼠单抗
- 免疫原Recombinant protein
- 偶联Non-conjugated
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性能
- 形态Liquid
- 浓度2 mg/mL.
- 存放说明Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles.
- 存储缓冲液1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.
- 亚型IgG1
- 纯化方式Protein A purified.
- 亚细胞定位Nucleus.
- 其它名称
- CBX 3 antibody
- CBX3 antibody
- CBX3_HUMAN antibody
more
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应用
WB: 1:500-1:2,000
IHC-P: 1:50-1:200
FC: 1:100-1:200
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Fig1: Western blot analysis of CBX3 on human CBX3 recombinant protein using anti-CBX3 antibody at 1/1,000 dilution.
Fig2: Western blot analysis of CBX3 on HEK293 (1) and CBX3-hIgGFc transfected HEK293 (2) cell lysate using anti-CBX3 antibody at 1/1,000 dilution.
Fig3: Immunohistochemical analysis of paraffin-embedded human ovarian cancer tissue using anti-CBX3 antibody. Counter stained with hematoxylin.
Fig4: Immunohistochemical analysis of paraffin-embedded human esophageal cancer tissue using anti-CBX3 antibody. Counter stained with hematoxylin.
Fig5: Flow cytometric analysis of A431 cells with CBX3 antibody at 1/100 dilution (green) compared with an unlabelled control (cells without incubation with primary antibody; red).
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